All interactions are traceable, auditable, and grounded in your real documents and data.

How It Works (At a Glance)

1. Ingest & Index
2. • Protocols, amendments, prior trials, regulatory guidance, SOPs, site manuals, and operational data are securely ingested and indexed.
3. Reason with GenAI + RAG
4. • GenAI handles drafting, explanation, and scenario analysis.
   • RAG keeps every recommendation tied to specific source texts and data.
5. Close the Loop
6. • Execution data feeds back into the Optimizer, improving future protocol design, feasibility estimates, and operational playbooks.

Business Value

• Faster, higher-quality protocol designFewer amendments, smoother start-up, and more feasible trials from day one.
• Better recruitment & retentionProtocols optimized for patient and site burden, with real-time operational support.
• Fewer deviations, stronger complianceSites get instant, grounded answers; sponsors get full traceability and audit readiness.
• A learning system, not a one-off toolEvery trial makes the “Clinical Trial Brain” smarter for the next.

Who It’s For

• Biopharma sponsors running multi-site trials
• CROs wanting differentiated, tech-enabled services
• Healthcare / life sciences teams on AWS looking to operationalize GenAI safely

The Solution: A “Clinical Trial Brain” Powered by GenAI + RAG

Propel builds a Generative AI + Retrieval-Augmented Generation (RAG) platform that sits across your clinical trial lifecycle:

• During Design – Trial Optimizer
• • Drafts and refines protocols using your historical trials, regulatory guidance, and internal SOPs
  • Scores complexity and burden for patients, sites, and operations
  • Forecasts recruitment and feasibility, and compares “what-if” protocol variants
  • Sandboxes amendments, showing impact on timelines, burden, and risk
• During Execution – Protocol Controller
• • Acts as a natural-language copilot for sites: “What’s allowed if this visit is late?”
  • Retrieves the exact protocol and guidance text behind every answer
  • Monitors deviations and patterns across sites in near real time
  • Suggests compliant, low-risk operational adjustments within defined guardrails

All interactions are traceable, auditable, and grounded in your real documents and data.

How It Works (At a Glance)

1. Ingest & Index
2. • Protocols, amendments, prior trials, regulatory guidance, SOPs, site manuals, and operational data are securely ingested and indexed.
3. Reason with GenAI + RAG
4. • GenAI handles drafting, explanation, and scenario analysis.
   • RAG keeps every recommendation tied to specific source texts and data.
5. Close the Loop
6. • Execution data feeds back into the Optimizer, improving future protocol design, feasibility estimates, and operational playbooks.

Business Value

• Faster, higher-quality protocol designFewer amendments, smoother start-up, and more feasible trials from day one.
• Better recruitment & retentionProtocols optimized for patient and site burden, with real-time operational support.
• Fewer deviations, stronger complianceSites get instant, grounded answers; sponsors get full traceability and audit readiness.
• A learning system, not a one-off toolEvery trial makes the “Clinical Trial Brain” smarter for the next.

Who It’s For

• Biopharma sponsors running multi-site trials
• CROs wanting differentiated, tech-enabled services
• Healthcare / life sciences teams on AWS looking to operationalize GenAI safely