The Problem
Clinical trials are slowed down and made more expensive by:
- Overly complex protocols that are hard to recruit and retain for
- Slow, manual amendment cycles
- Site teams wrestling with dense PDFs and inconsistent guidance
- Risky deviations whenever real life collides with rigid plans
Sponsors and CROs need a system that continuously optimizes trial design and execution—not just another static protocol document.
The Solution: A “Clinical Trial Brain” Powered by GenAI + RAG
Propel builds a Generative AI + Retrieval-Augmented Generation (RAG) platform that sits across your clinical trial lifecycle:
- During Design – Trial Optimizer
- Drafts and refines protocols using your historical trials, regulatory guidance, and internal SOPs
- Scores complexity and burden for patients, sites, and operations
- Forecasts recruitment and feasibility, and compares “what-if” protocol variants
- Sandboxes amendments, showing impact on timelines, burden, and risk
- During Execution – Protocol Controller
- Acts as a natural-language copilot for sites: “What’s allowed if this visit is late?”
- Retrieves the exact protocol and guidance text behind every answer
- Monitors deviations and patterns across sites in near real time
- Suggests compliant, low-risk operational adjustments within defined guardrails
All interactions are traceable, auditable, and grounded in your real documents and data.
How It Works (At a Glance)
- Ingest & Index
- Protocols, amendments, prior trials, regulatory guidance, SOPs, site manuals, and operational data are securely ingested and indexed.
- Reason with GenAI + RAG
- GenAI handles drafting, explanation, and scenario analysis.
- RAG keeps every recommendation tied to specific source texts and data.
- Close the Loop
- Execution data feeds back into the Optimizer, improving future protocol design, feasibility estimates, and operational playbooks.
Business Value
- Faster, higher-quality protocol designFewer amendments, smoother start-up, and more feasible trials from day one.
- Better recruitment & retentionProtocols optimized for patient and site burden, with real-time operational support.
- Fewer deviations, stronger complianceSites get instant, grounded answers; sponsors get full traceability and audit readiness.
- A learning system, not a one-off toolEvery trial makes the “Clinical Trial Brain” smarter for the next.
Who It’s For
- Biopharma sponsors running multi-site trials
- CROs wanting differentiated, tech-enabled services
- Healthcare / life sciences teams on AWS looking to operationalize GenAI safely